Associate Provost and Professor of Chemistry Bill Malachowski has been awarded a National Institute of Health grant to assist in developing better medications. The grant will support undergraduate and graduate research in the Chemistry Department for three years with a $362,500 award.
Project Title: The enantioselective synthesis of new phenanthridinone and carbazole analogs with quaternary and tertiary carbons using the Birch-Heck sequence
Project Summary: Vast amounts of chemical space are unexplored due to limitations in synthetic chemistry tools. The current chemical space for new drugs is heavily populated with flat aromatic structures that have a higher propensity for failure in clinical drug trials. The proposed project will create new synthetic tools to expeditiously construct complex structural motifs commonly found in successful therapeutic molecules.
Department of Chemistry
